Supplementation for Regenerative Treatments

In response to numerous questions from many of our stem cell/platelet rich plasma patients, we have compiled a list of the most common supplements that may be beneficial to the regenerative process. We also discuss briefly the supplements and medications that should not be taken during the regenerative therapies. These supplements are generally beneficial even for patients who do not undergo regenerative therapies. Some, like vitamin D, play an important role in pain transmission and perception. This is not a comprehensive list, and we are not nutritionists or endocrinologists. It is always a good idea to discuss the following dosages of supplementation with your primary care physician, your nutritionist, and/or your endocrinologist.
  • Vitamin D3 – check your Vitamin D levels to determine appropriate dosage. Target blood concentration is 40 nanograms/ml
  • Vitamin A – for most people, 15000 IU in the form of mixed carotenoids daily should be adequate. Use plant derived Vitamin A precursor called carotenoids. Check blood levels first.
  • Vitamin K2 – about 25 micrograms/day for most people and up to 100 micrograms/day if there are bone density issues or with older adults.
  • Zinc – 15 mg daily for most adults. Check your serum levels for zinc and copper first.
  • Omega 3 – try 300 mg of Krill oil daily for most adults. Test blood for C – reactive protein (CRP) levels to measure general level of inflammation in the body. If CRP is elevated, additional Omega 3 supplements and other anti–inflammatory herbs may be added.
  • CoQ10 (Coenzyme Q10) – 100 mg daily. It is fat soluble, should be taken with meals. If you are taking cholesterol lowering drugs such as statins, take extra CoQ10 supplementation, up to 200 mg daily. Statins tend to deplete the body of naturally occurring CoQ10.
  • Acetyl -L- carnitine – up to 500 mg daily
  • Methyl folate – 400 micrograms daily up to 1 mg, based on deficiency level. Check blood levels for homocysteine. Consume more green leafy vegetables.
  • Check hormone levels for thyroid hormones, testosterone, DHEA, estrogen, progesterone and IGF-1 as appropriate. Hormone imbalance hinders body’s regeneration abilities.
  • Above supplementation are suggestions and not a requirement for stem cell or PRP procedures.
  • Mg stand for milligrams, and mcg for micrograms; it is important to use correct dosages.
  • If you choose to use supplements, use them 1-2 weeks prior and 4-6 weeks after the procedure, except for omega 3 oils as listed on fourth note below.
  • Localized inflammation caused by stem cell and PRP procedures is part of the healing process and is beneficial and desired. Use of anti-inflammatory supplements can interfere with this process. Take high quality omega 3 oil, but not for at least one week before and one week after the procedure. This also applies to other natural anti-inflammatory substances commonly used such as boswellia, curcumin, grape seed extract, bilberry, licorice root and others, which may be present in some multi-vitami
  • Do not take any nonprescription anti-inflammatory (NSAIDS) two before and two weeks after the procedure. This includes aspirin, ibuprofen (Motrin/Advil), naproxen (Aleve), diclofenac, etodolac, meloxicam (Mobic), Celebrex, etc. Use Tylenol if needed.
  • If you are taking fiber supplements, they should not be taken at the same time as any prescription or non-prescription supplementation.
We are indebted to Mrs. Suzanne Taleghani and her research efforts into regenerative treatment supplementation.


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